Pathways
Glutathione Metabolism in N. meningitides MC58
Description:
Neisseria meningitidis is a causative agent of meningitis, and is responsible for considerable morbidity and mortality throughout the world. Most disease causing N. meningitidis strains belong to Serogroups A, B and C. Serogroup A strains are responsible for epidemic disease in developing countries, and Serogroup B and C strains are responsible for outbreaks of menigitis in the developed world. The 2,272,351-base pair genome of N. meningitidis Strain MC58 (Serogroup B), a causative agent of meningitis and se...
References:
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Metabolism and virulence in Neisseria meningitidis.
Front Cell Infect Microbiol. 2014 Aug 20;4:114. doi: 10.3389/fcimb.2014.00114. -
The Meningococcal Cysteine Transport System Plays a Crucial Role in Neisseria meningitidis Survival in Human Brain Microvascular Endothelial Cells.
mBio. 2018 Dec 11;9(6):e02332-18. doi: 10.1128/mBio.02332-18. -
Multiple Functions of Glutamate Uptake via Meningococcal GltT-GltM L-Glutamate ABC Transporter in Neisseria meningitidis Internalization into Human Brain Microvascular Endothelial Cells.
Infect Immun. 2015 Sep;83(9):3555-67. doi: 10.1128/IAI.00654-15. Epub 2015 Jun 22. -
Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure-Function Relationship and Its Biotechnological Applications.
Front Microbiol. 2021 Apr 9;12:641251. doi: 10.3389/fmicb.2021.641251.
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