Pathways
Glutathione Metabolism in M. musculus
Description:
The tripeptide Glutathione is part of an integrated antioxidant system that protects cells and tissues from oxidative damage. Oxidative stress can result from exposure to excessive amounts of endogenous and exogenous electrophiles (Ref.1). Glutathione exists in two forms. The antioxidant "reduced Glutathione" tripeptide is conventionally called Glutathione and abbreviated Gsh; the oxidized form is a sulfur-sulfur linked compound, known as Glutathione Disulfide or GSSG. The GSSG/Gsh ratio may be a sensitive indica...
References:
-
Genetically altered mice to evaluate glutathione homeostasis in health and disease.
Free Radic Biol Med. 2004 Nov 15; 37(10):1511-26. -
Expression of glutamate-cysteine ligase during mouse development.
Mol Reprod Dev. 2002 May; 62(1):83-91. -
Regulation of cellular glutathione.
Am J Physiol. 1989 Oct; 257(4 Pt 1):L163-73. -
gamma-L-glutamyltaurine.
Amino Acids. 2005 Apr 21.
You can view details of this pathway by subscribing:
9853 Pacific Heights Blvd.
Suite D., San Diego, CA 92121, USA
Tel: 858-224-2869
Fax: 858-205-1192
info@proteinlounge.com
Databases
Tools
Institutional License
Need our databases and tools to be availed by your whole university or institute? We recommend signing up for our Site License.
To set up a license, please contact: info@proteinlounge.com
Copyright © Protein Lounge Inc.
Terms & Conditions