Pathways
Glutathione Metabolism in B. pertussis
Description:
Bordetella is a Gram-negative Beta-proteobacteria that colonizes the respiratory tracts of mammals. It produces a complex array of adhesins, aggressins and toxins that are presumed to be important in the colonisation of its human host and in ensuring its survival and propagation. The organism also has highly sophisticated mechanisms for regulating virulence factor expression, in response to environmental signals or by reversible mutations. Bordetella pertussis, the etiologic agent of whooping cough, produces...
References:
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Environmental Origin of the Genus Bordetella.
Front Microbiol. 2017 Jan 24;8:28. doi: 10.3389/fmicb.2017.00028. -
Bordetella pertussis transmission.
Pathog Dis. 2015 Nov;73(8):ftv068. doi: 10.1093/femspd/ftv068. Epub 2015 Sep 14. -
Bordetella pertussis pathogenesis: current and future challenges.
Nat Rev Microbiol. 2014 Apr;12(4):274-88. doi: 10.1038/nrmicro3235. Epub 2014 Mar 10. -
Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure-Function Relationship and Its Biotechnological Applications.
Life Sci. 2005 Apr 22; 76(23):2681-97
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