Glutathione Metabolism in Y. pestis KIM biovar Mediaevalis

Description:

Glutathione is a tripeptide present in Yersinia sp., which is composed of Glutamate, Cysteine and Glycine, and has numerous important functions within cells. Yersinia sp. is responsible for disease syndromes ranging from gastroenteritis to plague. Y. pestis is categorized into three subtypes or biovars; Antiqua, Medievalis, and Orientalis, each associated with a major pandemic. The strain Y. pestis KIM belongs to biovar Mediaevalis and is associated with the second pandemic, including the Black Death (Ref.1).

Glutathion...

References:

Genome sequence of Yersinia pestis KIM.
Deng W, Burland V, Plunkett G 3rd, Boutin A, Mayhew GF, Liss P, Perna NT, Rose DJ, Mau B, Zhou S, Schwartz DC, Fetherston JD, Lindler LE, Brubaker RR, Plano GV, Straley SC, McDonough KA, Nilles ML, Matson JS, Blattner FR, Perry RD.
J Bacteriol. 2002 Aug;184(16):4601-11. doi: 10.1128/JB.184.16.4601-4611.2002.
Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure-Function Relationship and Its Biotechnological Applications.
Saini M, Kashyap A, Bindal S, Saini K, Gupta R.
Front Microbiol. 2021 Apr 9;12:641251. doi: 10.3389/fmicb.2021.641251.
Glutathione: a review on biotechnological production.
Li Y, Wei G, Chen J.
Appl Microbiol Biotechnol. 2004 Dec; 66(3):233-42.
Glutathione homeostasis and functions: potential targets for medical interventions.
Lushchak VI.
J Amino Acids. 2012;2012:736837. doi: 10.1155/2012/736837. Epub 2012 Feb 28.

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Glutathione Metabolism in Y. pestis KIM biovar Mediaevalis

Description:

References:

Genome sequence of Yersinia pestis KIM.

Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure-Function Relationship and Its Biotechnological Applications.

Glutathione: a review on biotechnological production.

Glutathione homeostasis and functions: potential targets for medical interventions.

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Institutional License

Pathways

Glutathione Metabolism in Y. pestis KIM biovar Mediaevalis

Description:

References:

Genome sequence of Yersinia pestis KIM.

Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure-Function Relationship and Its Biotechnological Applications.

Glutathione: a review on biotechnological production.

Glutathione homeostasis and functions: potential targets for medical interventions.

Databases

Tools

Institutional License

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