Pathways
Glutathione Metabolism in L. pneumophila Paris
Description:
Legionella pneumophila is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium of the genus Legionella that proliferates within alveolar macrophages, causing Legionnaires’ disease (Ref.1). It inhabits freshwater ecosystems, where it is present in biofilm or as planktonic form. L. pneumophila is mainly found associated with protozoa, which serve as protection from hostile environments and as replication niche. If inhaled within aerosols, L. pneumophila is also able to in...
References:
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Evolution of the Arsenal of Legionella pneumophila Effectors To Modulate Protist Hosts.
mBio. 2018 Oct 9;9(5):e01313-18. doi: 10.1128/mBio.01313-18. -
The Life Cycle of L. pneumophila: Cellular Differentiation Is Linked to Virulence and Metabolism.
Front Cell Infect Microbiol. 2018 Jan 19;8:3. doi: 10.3389/fcimb.2018.00003. -
Legionella pneumophila serogroup 1 strain Paris: endemic distribution throughout France.
J Clin Microbiol. 2003 Jul;41(7):3320-2. doi: 10.1128/JCM.41.7.3320-3322.2003. -
Current status and emerging role of glutathione in food grade lactic acid bacteria.
Microb Cell Fact. 2012 Aug 25;11:114. doi: 10.1186/1475-2859-11-114.
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