Pathways
Glutathione Metabolism in B. suis
Description:
Bacteria of the genus Brucella are Gram-negative facultative intracellular pathogens of various wild and domestic mammals and are able to cause brucellosis, a severe zoonotic infection affecting ruminants, pigs, dogs, rodents, and cetacean. Traditionally, three major species are distinguished by their predilections for certain animal hosts: Brucella abortus for cattle, Brucella melitensis for caprines, and Brucella suis for hogs. Whereas B. abortus is the livestock pathogen with the greatest economi...
References:
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The Intracellular Life Cycle of Brucella spp.
Microbiol Spectr. 2019 Mar;7(2):10.1128/microbiolspec.BAI-0006-2019. doi: 10.1128/microbiolspec.BAI-0006-2019. -
Oral vaccination with Brucella melitensis WR201 protects mice against intranasal challenge with virulent Brucella melitensis 16M.
Croat Med J. 2010 Aug;51(4):296-305. doi: 10.3325/cmj.2010.51.296. -
Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes.
Biochim Biophys Acta. 2013 May;1830(5):3217-66. doi: 10.1016/j.bbagen.2012.09.018. Epub 2012 Oct 2. -
Regulation of aminopeptidase N (EC 3.4.11.2; APN; CD13) by interferon-gamma on the HL-60 cell line.
Mol Aspects Med. 2009 Feb-Apr;30(1-2):1-12. doi: 10.1016/j.mam.2008.08.006. Epub 2008 Aug 30.
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