Pathways
Glutathione Metabolism in V. vulnificus YJ016
Description:
Vibrio vulnificus is an etiologic agent for severe human infection acquired through wounds or contaminated seafood. This is a lactose-fermenting, halophilic, Gram-negative, opportunistic pathogen, is found in estuarine environments and is associated with various marine species such as plankton, shellfish (Oysters, Clams, and Crabs), and finfish (Ref.1). V. vulnificus belong to the Gamma-group of Proteobacteria, and it shares morphological and biochemical characteristics with other human Vibrio pathogens, inc...
References:
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Vibrio vulnificus: new insights into a deadly opportunistic pathogen.
FEMS Microbiol Lett. 1999 May 15; 174(2):207-14 -
Vibrio vulnificus: An Environmental and Clinical Burden.
Front Microbiol. 2017 May 31;8:997. doi: 10.3389/fmicb.2017.00997. -
Regulation of glutathione synthesis.
Mol Aspects Med. 2009 Feb-Apr;30(1-2):42-59. doi: 10.1016/j.mam.2008.05.005. Epub 2008 Jun 14. -
Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis.
Cell Metab. 2021 Jan 5;33(1):174-189.e7. doi: 10.1016/j.cmet.2020.12.007. Epub 2020 Dec 22.
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