Pathways
Glycine and Serine Metabolism in H. pylori 26695
Description:
H. pylori (Helicobacter pylori) are Gram-negative, micro-aerophilic, spiral-shaped and flagellated bacteria that remains associated with Gastric inflammation and Peptic ulcer disease. As a human pathogen, H. pylori’s presence in the gastric mucosa is associated with Gastritis and is often implicated in Peptic ulceration and Mucosa-associated lymphoid tissue Lymphomas (Ref.1). The H. pylori genome is important for drug discovery and vaccine development and this is exemplified by the ge...
References:
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Helicobacter pylori: current status and future prospects.
Cells. 2020 Dec 25;10(1):27. doi: 10.3390/cells10010027. -
Pathogenesis of Helicobacter pylori infection.
Clin Microbiol Rev. 2006 Jul;19(3):449-90. doi: 10.1128/CMR.00054-05. -
L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels.
Microbiology. 2003 Aug;149(Pt 8):2023-30. -
Sensing phosphatidylserine in cellular membranes.
Sensors (Basel). 2011;11(2):1744-55. doi: 10.3390/s110201744. Epub 2011 Jan 28.
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