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Pathways

Glycine, Serine and Threonine Metabolism in C. albicans

Description:

Like many bacteria, yeast species can form biofilms on several surfaces. C. albicans (Candida albicans) colonizes in the surfaces of catheters, prostheses, and epithelia, forming biofilms that are extremely resistant to anti-fungal drugs. The protein Gcn4 (Transcriptional Activator Gcn4), a regulator of amino acid metabolism, is required for normal biofilm growth. The biochemical mechanisms including activatio[...]

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