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Glycine, Serine and Threonine Metabolism in T. denticola


The Gram-negative oral spirochete T. denticola (Treponema denticola) is predominantly associated with the incidence and severity of human periodontal disease. T. denticola is an obligate anaerobe commonly associated with an inflammation of gum tissue that frequently precedes bone resorbtion and subsequent tooth loss of humans. T. denticola lacks a traditional LPS (Lipopolysaccharide), as do many other Spirochetes, for which these are resistant to cationic peptide antibiotics as well as to h...




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