Pathways
Glycine, Serine and Threonine Metabolism in S. flexneri 2457T
Description:
Shigella is pathogenic only for humans and the strains are unusual among enteric bacteria in their ability to gain access to the epithelial cell cytosol, where they replicate and spread directly into adjacent cells. It causes disease by invading the epithelium of the colon, resulting in an intense acute inflammatory response. Shigella species are Gram-negative, non-sporulating and facultative anaerobes. S. flexneri (Shigella flexneri) lacks surface structures such as flagella, fimbriae, and cu...
References:
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Infections caused by Shigella flexneri recognized as food poisonings in Warmia and Mazury Voivodeship.
Przegl. Epidemiol. 2005;59(1):53-8. -
Shigella flexneri infection is dependent on villin in the mouse intestine and in primary cultures of intestinal epithelial cells.
Cell Microbiol. 2005 Aug;7(8):1109-16. -
Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T.
Infect. Immun. 2003 May;71(5):2775-86. Erratum in: Infect Immun. 2003 Jul;71(7):4223. -
Identification of novel immunogenic proteins of Shigella flexneri 2a by proteomic methodologies.
Vaccine. 2004 Jul 29;22(21-22):2750-6.
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