Pathways
Guillain-Barre Syndrome
Description:
GBS (Guillain-Barré Syndrome) is often known as post infectious, immune-mediated nerve injury. This syndrome results in inflammatory demyelination, characterized by acute weakness of the extremities and areflexia. The pathological features of GBS include inflammation, demyelination, and axonal damage in the PNS (Peripheral Nervous System) (Ref.1 & 2). AIDP (Acute Inflammatory Demyelinating Polyneuropathy) and AMAN (Acute Motor Axonal Neuropathy) are the common su...
References:
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Guillain-Barré Syndrome.
Mayo Clin Proc. 2017 Mar;92(3):467-479. doi: 10.1016/j.mayocp.2016.12.002. -
Beneficial or Harmful Role of Macrophages in Guillain-Barré Syndrome and Experimental Autoimmune Neuritis.
Mediators Inflamm. 2018 Apr 26;2018:4286364. doi: 10.1155/2018/4286364. -
Guillain-Barré syndrome.
Am Fam Physician. 2013 Feb 1;87(3):191-7. -
Guillain-Barré syndrome: pathogenesis, diagnosis, treatment and prognosis.
Nat Rev Neurol. 2014 Aug;10(8):469-82. doi: 10.1038/nrneurol.2014.121. Epub 2014 Jul 15.
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