Pathways
Hair Growth Cycle
Description:
The hair follicle is a three-dimensional tube, composed mainly of epithelial cells that protrude down through the epidermis and dermis of the skin, enveloping at its base the mesenchyme-derived dermal papilla. These hair follicle acts as a sensory organ and immunologic sentinel for the skin. Hairs detect mechanical stimuli above the surface of the skin, and the slightest bend in a hair activates Neuroreceptors in the follicle, relaying important sensory information to the Nervous System. The Langerhans' cells (Dendritic Antigen-...
References:
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Review of hair follicle dermal cells.
J Dermatol Sci. 2010 Jan;57(1):2-11. doi: 10.1016/j.jdermsci.2009.11.005. Review. -
In search of the "hair cycle clock": a guided tour.
Differentiation. 2004 Dec; 72(9-10):489-511. -
Hair Follicle Terminal Differentiation Is Orchestrated by Distinct Early and Late Matrix Progenitors.
Cell Rep. 2017 Apr 25;19(4):809-821. doi: 10.1016/j.celrep.2017.03.077. -
Resting no more: re-defining telogen, the maintenance stage of the hair growth cycle.
Biol Rev Camb Philos Soc. 2015 Nov;90(4):1179-96. doi: 10.1111/brv.12151. Epub 2014 Nov 19. Review.
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