Hematopoiesis is the process that generates blood cells of all lineages (Ref.1). The process of generation of blood cells begins in the early embryo and continues throughout life. Every day, billions of new blood cells are produced in the body, each one derived from a HSC (Hematopoietic Stem Cell). Because most mature blood stem cells have a limited life span, the ability of HSCs to perpetuate themselves through self-renewal and generate new blood cells for the lifetime of an organism is critical to sustaining life. Hematopoieti...
N Engl J Med. 2006 May 11; 354(19):2034-45. Review. No abstract available.
Oncogene. 2007 Oct 15; 26(47):6715-23. Review.
Recent Prog Horm Res. 2003; 58:283-95. Review.
Am J Pathol. 2006 Aug; 169(2):338-46. Erratum in: Am J Pathol. 2006 Nov; 169(5):1899.
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