Pathways
Immune Escape by Monkeypox Virus
Description:
Human monkeypox (MPX) is a zoonotic disease caused by the monkeypox virus (MPXV) affecting rodents and primates mostly in western and central Africa that incidentally causes disease in humans similar to smallpox, although with notably lower mortality. The current outbreak of the disease in various parts of the world is considered an epidemic and a new global threat. MPXV, a double-stranded D...
References:
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Monkeypox virus emerges from the shadow of its more infamous cousin: family biology matters.
Emerg Microbes Infect. 2022 Dec;11(1):1768-1777. doi: 10.1080/22221751.2022.2095309. -
Evasion of the Innate Immune Type I Interferon System by Monkeypox Virus.
J Virol. 2015 Oct;89(20):10489-99. doi: 10.1128/JVI.00304-15. Epub 2015 Aug 5. -
Analysis of the monkeypox virus genome. Virology.
2002 Jun 5;297(2):172-94. doi: 10.1006/viro.2002.1446. -
Monkeypox virus: a re-emergent threat to humans.
Virol Sin. 2022 Aug;37(4):477-482. doi: 10.1016/j.virs.2022.07.006. Epub 2022 Jul 9.
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