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Pathways

Inflammatory Bowel Disease

Description:

The gastrointestinal (GI) tract plays a central role in maintaining immune homeostasis, i.e., tolerance to non-pathogenic commensal bacteria, self-antigens, and food antigens, while also protecting the host against pathogenic organisms by mounting an inflammatory response. The fine line between tolerance and inflammation of the GI immune system, when disrupted, may result in diseases such as inflammatory bowel disease (IBD). IB[...]

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