Pathways
Interaction of Probiotics with Gut Immune System
Description:
The immune response is initiated by innate immunity following exposure to foreign substances or tissue injury. Innate immunity exerts protective roles in host homeostasis in part by priming adaptive immune responses against persisting insults and inducing inflammation. However, the unbalanced immune response leads to severe inflammation and uncontrolled tissue damage and disease. Sensing of the intestinal microbiota by the host mucosal immune system plays significant roles in maintaining intestinal homeostasis and inducing sy...
References:
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Probiotics and immune health.
Curr Opin Gastroenterol. 2011 Oct;27(6):496-501. doi: -
Probiotic mechanisms of action.
Ann Nutr Metab. 2012;61(2):160-74. doi: 10.1159/000342079. Epub 2012 Oct 2. Review. -
Mechanisms of Action of Probiotics.
Adv Nutr. 2019 Jan 1;10(suppl_1):S49-S66. doi: 10.1093/advances/nmy063. -
Gut microbiota and probiotics in modulation of epithelium and gut-associated lymphoid tissue function.
Int Rev Immunol. 2009;28(6):397-413. doi: 10.3109/08830180903215613. Review.
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