Pathways
Intracellular Calcium Signaling
Description:
Despite tremendous diversities in their expression, cellular activities in virtually all cell types are regulated by common intracellular signaling systems, and calcium is one important ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation. In response to adequate stimuli, [Ca2+]i (Intracellular Ca2+ concentration) increases, oscillates and decreases, leading to the activation, modulation and termination of cell functio...
References:
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Evolution of the Calcium-Based Intracellular Signaling System.
Genome Biol Evol. 2016 Jul 14;8(7):2118-32. doi: 10.1093/gbe/evw139. -
Mechanisms of capacitative calcium entry.
J Cell Sci. 2001 Jun;114(Pt 12):2223-9. Review. -
A role for voltage gated T-type calcium channels in mediating "capacitative" calcium entry?
Cell Calcium. 2006 Apr;39(4):357-66. Epub 2006 Jan 26. -
Calcium signaling.
Cold Spring Harb Perspect Biol. 2012 Jul 1;4(7):a011171. doi: 10.1101/cshperspect.a011171. No abstract available.
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