Pathways
Life Cycle of Plasmodium falciparum
Description:
Malaria is the world's largest parasitic disease, killing more people than any other communicable disease except Tuberculosis. Malaria is a major public health problem in more than 100 countries, inhabited by a total of some 2.4 billion people, or close to half of the world's population. Each year, 300–500 million people contract malaria and about 3 million die, most of which are children under five years old. In absolute numbers, malaria kills 3,000 children per day under the age of five. The total number of de...
References:
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Serial analysis of gene expression in Plasmodium falciparum reveals the global expression profile of erythrocytic stages and the presence of anti-sense transcripts in the malarial parasite.
Mol Biol Cell. 2001 Oct;12(10):3114-25. -
A parasite genome sheds light on an old enemy.
Nat Biotechnol. 2002 Nov;20(11):1098-9. -
Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity.
Nat Med. 2003 Jan;9(1):93-6. Epub 2002 Dec 16. -
Macromolecular transport in malaria-infected erythrocytes.
Novartis Found Symp. 1999;226:114-20; discussion 121-5.
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