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Pathways

Lipid Antigen Presentation by CD1

Description:

The CD1 (Thymocyte Antigen CD1) antigen presentation system presents lipid and glycolipid antigens to effector T-Cells, which have diverse roles in Antimicrobial responses, Antitumor immunity and in regulating the balance between Tolerance and Autoimmunity. CD1, a conserved family of MHC (Major Histocompatibility Complex)-like glycoproteins in mammals, specializes in capturing lipid rather than peptide antigen for presentati[...]

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