Pathways
MAPK Family Pathway
Description:
Protein kinases are ubiquitous enzymes that are able to modulate the activities of other proteins by adding phosphate groups to their tyrosine, serine, or threonine amino acids (phosphorylation). MAPKs (Mitogen-Activated Protein Kinases), which are activated by many different signals, belong to a large family of serine/threonine protein kinases that are conserved in organisms as diverse as yeast and humans. MAPKs deliver extracellular signals from activated receptors to various cellular compartments, notably the nucleus,...
References:
-
Mitogen-activated protein kinase signalling and ERK1/2 bistability in asthma.
Clin Exp Allergy. 2011 Feb;41(2):149-59. -
Mitogen activated protein kinases: a role in inflammatory bowel disease?
Clin Exp Immunol. 2009 Dec;158(3):272-80. -
Processive phosphorylation of ERK MAP kinase in mammalian cells.
Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12675-80. -
Differential regulation and properties of MAPKs.
Oncogene. 2007 May 14;26(22):3100-12.
You can view details of this pathway by subscribing:
9853 Pacific Heights Blvd.
Suite D., San Diego, CA 92121, USA
Tel: 858-224-2869
Fax: 858-205-1192
info@proteinlounge.com
Databases
Tools
Institutional License
Need our databases and tools to be availed by your whole university or institute? We recommend signing up for our Site License.
To set up a license, please contact: info@proteinlounge.com
Copyright © Protein Lounge Inc.
Terms & Conditions