Pathways
Mechanism of Protein Export in E. coli
Description:
The translocation of proteins from one compartment to another is an essential feature of cellular life. The proper functioning of extracytoplasmic proteins requires their export to, and productive folding in, the correct cellular compartment. Gram-negative bacteria secrete a wide range of proteins whose function includes biogenesis of organelles, such as Pili and flagella; nutrient acquisition; virulence; and efflux of drugs and other toxins. Export of these proteins to the bacterial surface involves transport across ...
References:
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Structural Basis of the Subcellular Topology Landscape of Escherichia coli.
Front Microbiol. 2019 Jul 24;10:1670. doi: 10.3389/fmicb.2019.01670. -
Mechanisms of protein export across the bacterial outer membrane.
J Bacteriol. 2005 Jul;187(13):4306-14. -
Protein export through the bacterial Sec pathway.
Nat Rev Microbiol. 2017 Jan;15(1):21-36. doi: 10.1038/nrmicro.2016.161. Epub 2016 Nov 28. -
Helical distribution of the bacterial chemoreceptor via colocalization with the Sec protein translocation machinery.
Mol Microbiol. 2006 May;60(4):894-906.
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