Diabetes mellitus is a chronic disease characterized by high blood glucose levels that requires long-term medical attention both to limit the development of its devastating complications and to manage them when they do occur. The pancreatic Beta-cell and its secretory product insulin are central in the pathophysiology of diabetes. There are two main types of diabetes, Type-I, which is insulin dependent, and Type-II, which is non-insulin dependent. Type-II diabetes is a complex and heterogeneous disease caused by both environm...
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