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Pathways

Mucosal Healing through Trefoil Factors

Description:

Epithelial continuity depends on a family of small, yet abundant, secreted proteins the TFFs (Trefoil Factors). TFFs are considered as 'Rapid Response' agents to mucosal injury; with up-regulation of expression in the early stages of mucosal repair. These peptides are involved in mucosal maintenance and repair through motogenic and anti-apoptotic activities. They also function as scatter factors, pro-invasive and ang[...]

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