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Mycothiol in Mycobacterium tuberculosis


Mycobacterium tuberculosis is a Gram-positive bacterium of the family Actinomycetes. M. tuberculosis is the causative agent of Tuberculosis (TB) which is the world’s second commonest cause of death next to HIV/AIDS. M. tuberculosis is adept at resisting stresses imposed by host immunity, including reactive oxygen species (ROS), reactive nitrogen species (RNS), and restricted access to oxygen, iron, and metabolizable sources of carbon. During adaptation to such stresses, M. tuberculosis alters ...




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