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Pathways

Netrin Signaling

Description:

Netrin1 (NTN1) Netrin1 is an evolutionarily conserved signaling protein , which functions as a common cue for axonal guidance and vascular patterning and is responsible for integrating regulatory cues from retinal neurons, glia and immune cells.Netrin1 deficiency may result in shunting of metabolic resources to optimize cell survival in viable retinal cells (Ref.1). Exposure to Netrin1 may lead to chemoattraction or chemor[...]

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