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PAK Pathway


PAKs (p21-Activated Protein Kinases) are a growing family of serine/threonine protein kinases, which are activated in response to extracellular signals and regulate cell shape and motility. PAKs regulate diverse cellular functions, including gene expression, cytoskeletal actin assembly, MAPK (Mitogen-Activated Protein Kinase) pathways, neurite outgrowth, cell cycle control, and cell apoptosis (Ref.1). The mammalian PAK family c[...]




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