Pathways
Pathogenesis of Rheumatoid Arthritis
Description:
Rheumatoid arthritis (RA) is a chronic symmetric polyarticular joint disease that primarily affects the small joints of the hands and feet. The inflammatory process is characterized by infiltration of inflammatory cells into the joints, leading to proliferation of synoviocytes and destruction of cartilage and bone.This is a chronic debilitating autoimmune disease of unknown etiology affecting diarthrodial joints. Although the disease is characterized by synovitis of the joints, tendon sheaths, and bursae, manifestations that ...
References:
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Rheumatoid Arthritis: Early diagnosis and treatment outcomes.
Caspian J Intern Med. 2011 Winter;2(1):161-70. -
Rheumatoid arthritis: what do MRI and ultrasound show.
J Ultrason. 2017 Mar;17(68):5-16. doi: 10.15557/JoU.2017.0001. Epub 2017 Mar 31. -
Immunopathogenesis of Rheumatoid Arthritis.
Immunity. 2017 Feb 21;46(2):183-196. doi: 10.1016/j.immuni.2017.02.006. Review. -
A cytokine-centric view of the pathogenesis and treatment of autoimmune arthritis.
J Interferon Cytokine Res. 2011 Dec;31(12):927-40. doi: 10.1089/jir.2011.0094. Review.
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