Pathways
Phagocytosis of Microbes
Description:
Phagocytosis is an important process for nutrition in unicellular organisms, while in multicellular organisms it is found in specialized cells called phagocytes. Phagocytosis consists in recognition and ingestion of particles larger than 0.5 𝜇m into a plasma membrane derived vesicle, known as phagosome. Phagocytes can ingest microbial pathogens, but importantly also apoptotic cells. In this way, they contribute to the clearance of billions of cells that are turned over every day. Thus phagocytosis becomes essential not o...
References:
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Phagocytosis: A Fundamental Process in Immunity.
Biomed Res Int. 2017;2017:9042851. doi: 10.1155/2017/9042851. Epub 2017 Jun 12. Review. -
Phagocytosis: a repertoire of receptors and Ca(2+) as a key second messenger.
Biosci Rep. 2008 Oct; 28(5):287-98. doi: 10.1042/BSR20080082. Review. Erratum in: Biosci Rep. 2014; 34(4):e00128c. -
Phagocytosis: An Immunobiologic Process.
Immunity. 2016 Mar 15; 44(3):463-475. doi: 10.1016/j.immuni.2016.02.026. Review. -
Strategic targets of essential host-pathogen interactions.
Respiration. 2005 Jan-Feb; 72(1):9-25. Review.
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