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Phosphatidylcholine Biosynthesis in S. cerevisiae


PC (Phosphatidylcholine) is the most abundant Phospholipid in the yeast S. cerevisiae (Saccharomyces cerevisiae) and the major Phospholipid present in eucaryotic cell membranes. It serves as a major structural component of cellular membranes and as a source of several lipid messengers. There are two pathways for PC synthesis in yeast, the CDP-Choline (Cytidine Diphosphate-Choline) pathway (a part of Kennedy Pathway) and the CDP-DAG (Cytidine Diphosphate-Diacylglycerol). Both pathways function to synth...



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