Atherosclerosis, the pathological basis of CAD (Coronary Artery Disease) and Ischemic Stroke, is the commonest cause of death and disability in the western world. Atherosclerosis is a multifactorial, highly complex disease with numerous aetiologies simultaneously and sequentially collaborating in subtle ways to affect lesion development, progression and maturation to an advanced, disease-provoking entity (Ref.1). The lesion, or Atheroma, is an inflammatory site composed of a necrotic lipid-rich core, modified vascular endotheliu...
References:
-
Di Pietro M, Filardo S, De Santis F, Sessa R.
Int J Mol Sci. 2013 Jul 19;14(7):15105-20. doi: 10.3390/ijms140715105. Review.
-
Rezaee-Zavareh MS, Tohidi M, Sabouri A, Ramezani-Binabaj M, Sadeghi-Ghahrodi M, Einollahi B.
ARYA Atheroscler. 2016 Jan;12(1):41-9. Review.
-
Honarmand H.
Interdiscip Perspect Infect Dis. 2013;2013:941392. doi: 10.1155/2013/941392. Epub 2013 Jul 17.
-
McCully KS.
Front Aging Neurosci. 2017 Oct 6;9:324. doi: 10.3389/fnagi.2017.00324. eCollection 2017. Review.
You can view details of this pathway by subscribing: