Pathways
Poliovirus Replication Cycle
Description:
Poliovirus is a member of the Picornaviridae family, which includes a number of significant pathogens of humans (e.g., Rhinoviruses, Coxsackieviruses, Echoviruses, Enteroviruses, and Hepatitis-A virus) and livestock (e.g., foot-and-mouth disease viruses). Poliovirus has three known serotypes: PV1, PV2, and PV3 and all three serotypes can cause poliomyelitis, a paralytic disease resulting from the destruction of motor neurons in the CNS (Central Nervous System )(Ref.1). All the three serotypes of Poliovirus recognize a common ...
References:
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Poliomyelitis: historical facts, epidemiology, and current challenges in eradication.
Neurohospitalist. 2014 Oct;4(4):223-9. doi: 10.1177/1941874414533352. -
Poliovirus Receptor: More than a simple viral receptor.
Virus Res. 2017 Oct 15;242:1-6. doi: 10.1016/j.virusres.2017.09.001. Epub 2017 Sep 8. -
Innate host barriers to viral trafficking and population diversity: lessons learned from poliovirus.
Adv Virus Res. 2010;77:85-118. doi: 10.1016/B978-0-12-385034-8.00004-1. -
Virus interactions with bacteria: Partners in the infectious dance.
PLoS Pathog. 2020 Feb 11;16(2):e1008234. doi: 10.1371/journal.ppat.1008234.
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