Pathways
H. pylori Activated Signaling
Description:
Helicobacter pylori is a gram negative bacterium that causes chronic inflammation in essentially all hosts, a process that increases the risk of developing peptic ulceration, distal gastric adenocarcinoma, and gastric mucosal lymphoproliferative disease. This bacterium also is the most common cause of ulcers worldwide. H. pylori infection is most likely acquired by ingesting contaminated food and water and through person to person contact. The infection is more common in crowded living conditions with poor sanitation. Infecte...
References:
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An Update on Helicobacter pylori as the Cause of Gastric Cancer.
Gastrointest Tumors. 2014 Aug;1(3):155-65. doi: 10.1159/000365310. Epub 2014 Jul 18. Review. -
Virulence Factors of Helicobacter pylori: A Review.
Clin Med Insights Gastroenterol. 2014 Mar 27;7:9-17. doi: 10.4137/CGast.S13760. eCollection 2014. Review. -
Immune responses to Helicobacter pylori infection.
World J Gastroenterol. 2014 May 21;20(19):5583-93. doi: 10.3748/wjg.v20.i19.5583. Review. -
Helicobacter pylori sensitizes TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human gastric epithelial cells through regulation of FLIP.
Cell Death Dis. 2014 Mar 6;5:e1109. doi: 10.1038/cddis.2014.81.
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