Pathways
Retinol Metabolism in Human Liver
Description:
Vitamin-A (all-trans-Retinol), one of the essential micronutrient in the human is obtained chiefly in form of Retinyl Esters from meat, and Carotenoids, such as Beta-Carotene, from plant tissue. Beta-carotene and other Carotenoids are converted by the body into Retinol and are referred to as Provitamin-A Carotenoids. Hundreds of different Carotenoids are synthesized by plants, but only about 10 percent of them are Provitamin-A Carotenoids (Ref.1). The main site for synthesis and storage of Vitamin-A is in the liver. The pRBPs (P...
References:
-
Absorption of vitamin A and carotenoids by the enterocyte: focus on transport proteins.
Nutrients. 2013 Sep 12;5(9):3563-81. doi: 10.3390/nu5093563. Review. -
A genetic clog in the vitamin A transport machinery.
Cell. 2015 Apr 23;161(3):435-437. doi: 10.1016/j.cell.2015.04.020. -
Retinol and retinyl esters: biochemistry and physiology.
J Lipid Res. 2013 Jul;54(7):1731-43. doi: 10.1194/jlr.R037648. Epub 2013 Apr 26. Review. -
Genetic Variations Associated with Vitamin A Status and Vitamin A Bioavailability.
Nutrients. 2017 Mar 8;9(3). pii: E246. doi: 10.3390/nu9030246. Review.
You can view details of this pathway by subscribing:
9853 Pacific Heights Blvd.
Suite D., San Diego, CA 92121, USA
Tel: 858-224-2869
Fax: 858-205-1192
info@proteinlounge.com
Databases
Tools
Institutional License
Need our databases and tools to be availed by your whole university or institute? We recommend signing up for our Site License.
To set up a license, please contact: info@proteinlounge.com
Copyright © Protein Lounge Inc.
Terms & Conditions