Pathways
Rotavirus Induced Diarrhea
Description:
Acute gastroenteritis is among the most common illnesses of humankind, and its associated morbidity and mortality are greatest among those at the extremes of age, children and the elderly. In developing countries, gastroenteritis is a common cause of death in children that can be linked to a wide variety of pathogens. The mammalian gastrointestinal epithelium is the largest surface area contacting the external environment. It is made up of five major cell types enterocytes, mucus-secreting goblet...
References:
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Inflammatory and oxidative stress in rotavirus infection.
World J Virol. 2016 May 12;5(2):38-62. doi: 10.5501/wjv.v5.i2.38. -
Detection of an unusual G8P[8] rotavirus in a Rotarix-vaccinated child with acute gastroenteritis using Nanopore MinION sequencing: A case report.
Medicine (Baltimore). 2020 Oct 2;99(40):e22641. doi: 10.1097/MD.0000000000022641. -
Structural Insights into Rotavirus Entry.
Adv Exp Med Biol. 2019;1215:45-68. doi: 10.1007/978-3-030-14741-9_3. -
Rotavirus infection.
Nat Rev Dis Primers. 2017 Nov 9;3:17083. doi: 10.1038/nrdp.2017.83.
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