Pathways
Serine Metabolism in C. tetani E88
Description:
Tetanus disease is one of the most dramatic and globally prevalent diseases of humans and vertebrate animals. The manifestation of the disease, spastic paralysis, is caused by the second most poisonous substance known, the Tetanus toxin (Ref.1). The causative agent of Tetanus disease is C. tetani (Clostridium tetani), an anaerobic Gram-positive, spore-forming bacterium, whose natural habitat is soil, dust, and the intestinal tracts of various animals and which enters the host through wound sites. Comparative genomics reveal...
References:
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Clostridial neurotoxins.
J. Neurol. Neurosurg. Psychiatry. 2004 Sep;75 Suppl 3:iii35-9. -
Effect of medium composition on the production of tetanus toxin by Clostridium tetani.
Biotechnol. Prog. 2005 May-Jun;21(3):756-61. -
Clostridium tetani Is a phospholipase (lecithinase)-producing bacterium.
J. Clin. Microbiol. 2005 Apr;43(4):2024-5. -
Tetanus in pregnancy.
Am. J. Perinatol. 2004 May;21(4):173-82.
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