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Pathways

siRNA Pathway in Drosophila and S.pombe

Description:

siRNAs (Small interfering RNAs) have gained much attention for their powerful ability to suppress gene expression. Introduction of dsRNA (double-stranded RNA), that are homologous in sequence to a gene, has proven to suppress that gene’s expression through a process known as RNAi (RNA interference). The basic mechanism behind RNAi is the breaking of a dsRNA matching a specific gene sequence into siRNA. These siRNAs are [...]

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