Pathways
Skin Blistering Disease
Description:
A blister (bulla) is a bubble of fluid that forms beneath a thin layer of dead skin. The fluid is a mixture of water and proteins that oozes from injured tissue. Blisters most commonly form in response to a specific injury, such as a burn or irritation, and usually involve only the topmost layers of skin. These blisters heal quickly, usually without leaving a scar. Blisters that develop as part of a systemic (bodywide) disease may start in the deeper layers of the skin and cover widespread areas. These blisters heal more slow...
References:
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Autoimmune blistering diseases in children.
Semin Cutan Med Surg. 2010 Jun;29(2):85-91. -
Overview of epidermolysis bullosa.
J Dermatol. 2010 Mar;37(3):214-9. -
Apoptotic pathways in pemphigus.
Dermatol Res Pract. 2010;2010:456841. Epub 2010 Jun 15. -
Adrenergic and cholinergic control in the biology of epidermis: physiological and clinical significance.
J Invest Dermatol. 2006 Sep;126(9):1948-65.
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