Pathways
Syncytium Formation by Human Respiratory Syncytial Virus
Description:
Human respiratory syncytial virus (RSV) is one of the most common viruses to infecting both children and adults, especially the elderly. RSV infection causes an upper respiratory infection in adults whereas in young children RSV causes bronchiolitis with small airway obstruction. It may progress to pneumonia, respiratory failure, apnea, and death (Ref.1).
RSV is a single-stranded, negative-strand, RNA virus belonging to the Paramyxoviridae family, and is in the genus Pneumovirus. The str...
References:
-
Preventing Pediatric Respiratory Syncytial Virus Infection.
Pediatr Ann. 2018 Sep 1;47(9):e371-e376. doi: 10.3928/19382359-20180816-01. -
RAGE inhibits human respiratory syncytial virus syncytium formation by interfering with F-protein function.
J Gen Virol. 2013 Aug;94(Pt 8):1691-1700. doi: 10.1099/vir.0.049254-0. Epub 2013 Apr 4. -
Syncytia Induction by Clinical Isolates of Human Respiratory Syncytial Virus A.
Intervirology. 2017;60(1-2):56-60. doi: 10.1159/000480014. Epub 2017 Sep 5. -
The Molecular Basis of Viral Inhibition of IRF- and STAT-Dependent Immune Responses.
Front Immunol. 2019 Jan 8;9:3086. doi: 10.3389/fimmu.2018.03086. eCollection 2018. Review.
You can view details of this pathway by subscribing:
9853 Pacific Heights Blvd.
Suite D., San Diego, CA 92121, USA
Tel: 858-224-2869
Fax: 858-205-1192
info@proteinlounge.com
Databases
Tools
Institutional License
Need our databases and tools to be availed by your whole university or institute? We recommend signing up for our Site License.
To set up a license, please contact: info@proteinlounge.com
Copyright © Protein Lounge Inc.
Terms & Conditions