Pathways
Taurine and Hypotaurine Metabolism
Description:
Taurine is a nonprotein Amino acid. It is an end product of L-Cysteine metabolism and the principal free intracellular Amino acid in many tissues of humans and other animal species. Taurine is present in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. It is classified as a conditionally essential Amino acid important during mammalian development because it is necessary to be supplied in the diet of infants for normal retinal and brain development. Taurine is different from...
References:
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Review: taurine: a "very essential" amino acid.
Mol Vis. 2012;18:2673-86. Epub 2012 Nov 12. -
Physiological significance of the taurine transporter and taurine biosynthetic enzymes in 3T3-L1 adipocytes.
Amino Acids. 2009 May;37(1):55-63. doi: 10.1007/s00726-008-0202-y. Epub 2008 Nov 15. -
Antioxidant properties of sulfinates: protective effect of hypotaurine on peroxynitrite-dependent damage.
J Biol Chem. 2011 Sep 16;286(37):32002-10. doi: 10.1074/jbc.M111.253344. Epub 2011 Jul 21. -
Taurine: the appeal of a safe amino acid for skeletal muscle disorders.
J Transl Med. 2015 Jul 25;13:243. doi: 10.1186/s12967-015-0610-1.
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