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Tec Kinases Signaling


Nonreceptor PTKs (Protein Tyrosine Kinases) are essential for the development and activation of B-Cells and T-Cells. The  Tec  kinases represent the second largest family of mammalian non-RTKs (Receptor Tyrosine Kinases), which are activated in blood cells by stimulation of Cytokine Receptors, Lymphocyte surface antigens, GPCR (G-Protein Coupled Receptors), receptor type PTKs, or Integrins (Ref.1).  Tec  f[...]




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