The
H. pylori (
Helicobacter pylori) J99 strains are Gram-negative, micro-aerophilic, spiral-shaped and flagellated bacteria, are associated with the pathogenesis of Gastric inflammation and Peptic ulcer disease (Ref.1). Presence of
H. pylori J99 in the gastric mucosa is associated with Duodenal ulcers. The
H. pylori genome is important for drug discovery and vaccine development and this is exemplified by the genome analysis of not only
H. pylori Strain 26695 but also H. pylori J99.
References:
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Itoh T, Seno H, Kita T, Chiba T, Wakatsuki Y.
Scand. J. Gastroenterol. 2005 Jun;40(6):641-7.
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Roche N, Angstrom J, Hurtig M, Larsson T, Boren T, Teneberg S.
Infect. Immun. 2004 Mar;72(3):1519-29.
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Lee KH, Cho MJ, Yamaoka Y, Graham DY, Yun YJ, Woo SY, Lim CY, Ko KS, Kim BJ, Jung HC, Lee WK, Rhee KH, Kook YH.
J. Clin. Microbiol. 2004 Aug;42(8):3518-24.
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Yahiro K, Wada A, Yamasaki E, Nakayama M, Nishi Y, Hisatsune J, Morinaga N, Sap J, Noda M, Moss J, Hirayama T.
J. Biol. Chem. 2004 Dec 3;279(49):51013-21.
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