Teeth develop as ectodermal appendages in vertebrate embryos, and their early development resembles morphologically as well as molecularly other organs such as Hairs and Glands. Interactions between the Ectoderm and underlying Mesenchyme constitute a central mechanism regulating the morphogenesis of all these organs. Central features of Tooth morphogenesis are the formation of the Epithelial Placode, the budding of the Epithelium, the condensation of Mesenchyme around the bud, and the folding and growth of the Epitheli...
Cold Spring Harb Perspect Biol. 2012 Apr 1;4(4):a008425.
Physiol Rev. 2017 Jul 1;97(3):939-993. doi: 10.1152/physrev.00030.2016.
J Dent Res. 2006 Jun;85(6):505-9.
J Biol Chem. 2006 Feb 24;281(8):5008-16. Epub 2005 Dec 19.
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