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Pathways

Transendothelial Migration of Leukocytes

Description:

The endothelium functions as a semipermeable barrier, regulating tissue fluid homeostasis and transmigration of leukocytes and providing essential nutrients across the vessel wall. Transport of plasma proteins and solutes across the endothelium involves two different routes: one transcellular, via caveolae-mediated vesicular transport, and the other paracellular, through interendothelial junctions. The permeability of the endot[...]

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