Pathways
UVC-Induced MAPK Signaling
Description:
Ultraviolet radiation (UVR) is an electromagnetic radiation that is shorter in wavelength than visible light but longer than X-rays. It falls in the range of 100nm to 400nm and is the most important environmental carcinogen leading to the development of skin cancers. UVR is divided into at least three different categories based on wavelength that includes ultraviolet C (UVC; 100–280 nm), ultraviolet B (UVB; 280–320 nm) and ultraviolet A (UVA; 320–400nm). The energy level of UV light is inversely ...
References:
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Roles of UVA radiation and DNA damage responses in melanoma pathogenesis.
Environ Mol Mutagen. 2018 Jun;59(5):438-460. doi: 10.1002/em.22176. Epub 2018 Feb 21. -
Functional genomics of UV radiation responses in human cells.
Mutat Res. 2004 May 18;549(1-2):65-78. -
UVA, UVB and UVC induce differential response signaling pathways converged on the eIF2α phosphorylation.
Photochem Photobiol. 2011 Sep-Oct;87(5):1092-104. doi: 10.1111/j.1751-1097.2011.00963.x. Epub 2011 Aug 16. -
UV-induced signaling pathways associated with corneal epithelial cell apoptosis.
Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5102-9. doi: 10.1167/iovs.03-0591.
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