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Pathways

VEGF Family Ligands and Receptor Interactions

Description:

Angiogenesis and lymphangiogenesis, the growth of new blood vessels from preexisting ones, are important processes during embryonic development, tissue growth, wound healing, and several pathological conditions. Several molecules are important for angiogenesis, most important being vascular endothelial growth factor (VEGF) family members and their corresponding receptors. VEGF belongs to the PDGF supergene family characterized by 8 conserved cysteines and functions as a homodimer structure. In mammals, the VEGF family consists o...

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