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Pathways

VPS34-PI3K Signaling in Saccharomyces cerevisiae

Description:

PI3Ks (Phosphoinositide-3 Kinases) are heterodimeric lipid kinases that are composed of a regulatory and catalytic subunit that are encoded by different genes. The phosphorylated lipid phosphatidylinositol 3-phosphate (PtdIns3P) is an important signaling molecule and has been found to localize to endosomes, multivesicular bodies, phagosomes, midbodies, peroxisomes and omegasomes. The generated PtdIns3P attracts PtdIns3P-binding[...]

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