Pathways
Yersinia Infection
Description:
Yersinia pestis, is a facultative intracellular a gram-negative bacillus responsible for causing bubonic plague (Ref.1). Apart from Y. pestis, two other pathogenic Yersinia species, Yersinia enterocolitica, Y. pseudotuberculosis, are known to infect human and animal hosts and cause a variety of intestinal and septicemic diseases. All three species harbor a virulence plasmid, which encodes a type III secretion system (T3SS) for s...
References:
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Yersinia pestis: mechanisms of entry into and resistance to the host cell.
Front Cell Infect Microbiol. 2013 Dec 24;3:106. doi: 10.3389/fcimb.2013.00106. -
Pathogenesis of Y. enterocolitica and Y. pseudotuberculosis in Human Yersiniosis.
J Pathog. 2011;2011:182051. doi: 10.4061/2011/182051. Epub 2011 Sep 12. -
Life After Secretion-Yersinia enterocolitica Rapidly Toggles Effector Secretion and Can Resume Cell Division in Response to Changing External Conditions.
Front Microbiol. 2019 Sep 13;10:2128. doi: 10.3389/fmicb.2019.02128. -
The Yersinia pestis type III secretion system: expression, assembly and role in the evasion of host defenses.
Immunol Res. 2013 Dec;57(1-3):237-45. doi: 10.1007/s12026-013-8454-3.
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