Pathways
ZIKA Virus Infection And Host Response
Description:
Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family, which can cause microcephaly, a birth defect where a baby's head is smaller than usual. Additionally, it is associated with Guillain-Barré syndrome, a neurological disorder that could lead to paralysis and even death. Zika virus illness has been described as self-limited and moderate in severity with the common findings of malaise, headache, fever, joint aches, a maculopapular rash, and inflammation of the conjunctiva. However, an alarming number of birth de...
References:
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The IFITMs Inhibit Zika Virus Replication.
Cell Rep. 2016 Jun 14;15(11):2323-30. doi: 10.1016/j.celrep.2016.05.074. Epub 2016 Jun 3. -
Overview of Zika virus (ZIKV) infection in regards to the Brazilian epidemic.
Braz J Med Biol Res. 2016;49(5):e5420. doi: 10.1590/1414-431X20165420. Epub 2016 Apr 29. Review. -
Biology of Zika Virus Infection in Human Skin Cells.
J Virol. 2015 Sep;89(17):8880-96. doi: 10.1128/JVI.00354-15. Epub 2015 Jun 17. -
Zika Virus: the Latest Newcomer.
Front Microbiol. 2016 Apr 19;7:496. doi: 10.3389/fmicb.2016.00496. eCollection 2016. Review.
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