• info@proteinlounge.com

Pathways

Metabolic Pathways

Displaying 145 to 156 (of 291 pathways)

Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor. It is ubiquitous in animals, plants, and microorganisms, and being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine and has numerous important functions within the Mycobacterium cells. Mycobacteria are Gram-positive, non-motile, pleomorphic rods shaped bacteria related to the Actinomyces. Most Mycobacteria are found in habitats such as water or soil. However, a few are intracellular pathogens of animals and humans. Mycobacterium tuberculosis CDC1551 is hyper virulent and is responsible for outbreak of tuberculosis. This strain is not more virulent than other M. tuberculosis[..]

Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor. It is ubiquitous in animals, plants, and microorganisms, and being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine and has numerous important functions within the Mycobacterium cells. Mycobacteria are Gram-positive, non-motile, pleomorphic rods shaped bacteria related to the Actinomyces. Most Mycobacteria are found in habitats such as water or soil. However, a few are intracellular pathogens of animals and humans. M. tuberculosis causes the disease known as tuberculosis. It has the potential to manufacture all of the machinery necessary to synthesize all its essential[..]

The tripeptide Glutathione is part of an integrated antioxidant system that protects cells and tissues from oxidative damage. Oxidative stress can result from exposure to excessive amounts of endogenous and exogenous electrophiles (Ref.1). Glutathione exists in two forms. The antioxidant "reduced Glutathione" tripeptide is conventionally called Glutathione and abbreviated Gsh; the oxidized form is a sulfur-sulfur linked compound, known as Glutathione Disulfide or GSSG. The GSSG/Gsh ratio may be a sensitive indicator of oxidative stress. Glutathione has potent electron-donating capacity. The reducing power of Gsh is a measure of its free-radical scavenging, electron-donating, and sulfhydryl-donating capacity. Reducing power is also the key to the multiple[..]

Nitrosomonas europaea is a Gram-negative obligate chemolithoautotroph, which derives all its energy and reductant for growth from the aerobic oxidation of ammonia to nitrite. The bacterium participates in the biogeochemical Nitrogen cycle in the process of nitrification (Ref.1 & 2). Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor. It is ubiquitous in all organisms including microorganisms like N. europaea. It is a tripeptide composed of Glutamate, Cysteine and Glycine, and has numerous important functions within cells. Being water soluble, it is found mainly in the cell cytosol and other aqueous phases of the living system. It is homeostatically controlled, both inside the cell and outside and often attains millimolar levels inside[..]

Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor. It is ubiquitous in animals, plants, and microorganisms, and being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine that has numerous important functions within cells. Glutathione is homeostatically controlled, both inside the cell and outside. It often attains millimolar levels inside cells, which makes it one of the most highly concentrated intracellular antioxidants. Glutathione exists in two forms. The antioxidant "reduced Glutathione" tripeptide is conventionally called Glutathione and abbreviated Gsh; the oxidized form is a sulfur-sulfur linked compound, known as[..]

Neisseria meningitidis is a causative agent of meningitis, and is responsible for considerable morbidity and mortality throughout the world. Most disease-causing N. meningitidis strains belong to Serogroups A, B and C. Serogroup A strains are responsible for epidemic disease in developing countries, and Serogroup B and C strains are responsible for outbreaks of menigitis in the developed world. The 2,272,351-base pair genome of N. meningitidis Strain MC58 (Serogroup B), a causative agent of meningitis and septicemia, contains 2158 predicted coding regions, 1158 (53.7%) of which are responsible for biological roles (Ref.1). N. meningitidis resides in its natural habitat within the nasopharyngeal tract of humans.Glutathione metabolism in N. meningitidis involves both the[..]

Neisseria meningitidis is a causative agent of meningitis, and is responsible for considerable morbidity and mortality throughout the world. Most disease-causing N. meningitidis strains belong to Serogroups A, B and C. Serogroup A strains are responsible for major epidemics and pandemics of meningococcal disease, and therefore most of the morbidity and mortality associated with this disease, and Serogroup B and C strains are responsible for outbreaks of menigitis in the developed world. N. meningitidis resides in its natural habitat within the nasopharyngeal tract of humans. These meningococci are opportunistic pathogens that colonize the nasopharynges and oropharynges of asymptomatic carriers. They occasionally gain access to the blood, and subsequently to the[..]

Pseudomonas aeruginosa is a Gram-negative, aerobic rod, belonging to the bacterial family Pseudomonadaceae and is one of the top three causes of opportunistic human infections. It is a versatile bacterium that grows in soil, marshes and coastal marine habitats, as well as on plant and animal tissues. It occurs regularly on the surfaces of plants and occassionally on the surfaces of animals. The bacterium is an opportunistic pathogen and hence, exploits some break in the host defenses to initiate an infection. It causes urinary tract infections, respiratory system infections, dermatitis, soft tissue infections, bacteremia, bone and joint infections, gastrointestinal infections and a variety of systemic infections, particularly in patients with severe burns and in cancer[..]

The malaria parasite Plasmodium falciparum is still a major threat to human health in the non-industrialized world mainly due to the increasing incidence of drug resistance. Infection with P. falciparum leads to increased oxidative stress in red blood cells, implying that the parasite requires efficient antioxidant and redox systems to prevent damage caused by ROS (Reactive Oxygen Species). P. falciparum possess functional thioredoxin and Glutathione systems. Thioredoxin Reductase, the first step of the Thioredoxin Redox Cycle, and Gamma-Glutamylcysteine Synthetase, the rate-limiting step of Glutathione synthesis, are essential for parasite survival. The mRNA levels of Gamma-Glutamylcysteine Synthetase are elevated in parasites that are oxidatively stressed,[..]

Photorhabdus is the only known terrestrial bioluminescent bacteria. Most members of the Photorhabdus are however insect pathogens that live in a strict symbiotic relationship within the digestive tract of entomopathogenic nematodes. Photorhabdus luminescens is a symbiont of nematodes and a broad-spectrum insect pathogen. It encodes a large number of adhesins, toxins, hemolysins, proteases and lipases, and contains a wide array of antibiotic synthesizing genes. These proteins likely play a role in the elimination of competitors, host colonization, invasion and bioconversion of the insect cadaver, making P. luminescens a promising model for the study of symbiosis and host-pathogen interactions (Ref.1). Glutathione metabolism in P. luminescens occurs within cells in two[..]

Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor. It is ubiquitous in animals, plants, and microorganisms, and being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine that has numerous important functions within cells. Glutathione is homeostatically controlled, both inside the cell and outside. It often attains millimolar levels inside cells, which makes it one of the most highly concentrated intracellular antioxidants. Glutathione exists in two forms. The antioxidant "reduced Glutathione" tripeptide is conventionally called Glutathione and abbreviated Gsh; the oxidized form is a sulfur-sulfur linked compound, known as[..]

Glutathione is a sulfhydryl (-SH) antioxidant, antitoxin, and enzyme cofactor. It is ubiquitous in animals, plants, and microorganisms, and being water soluble is found mainly in the cell cytosol and other aqueous phases of the living system. Glutathione is a tripeptide composed of Glutamate, Cysteine and Glycine that has numerous important functions within cells. Glutathione is homeostatically controlled, both inside the cell and outside. It often attains millimolar levels inside cells, which makes it one of the most highly concentrated intracellular antioxidants. Glutathione exists in two forms. The antioxidant "reduced Glutathione" tripeptide is conventionally called Glutathione and abbreviated Gsh; the oxidized form is a sulfur-sulfur linked compound, known as[..]

Displaying 145 to 156 (of 291 pathways)
logo

 

9853 Pacific Heights Blvd.
Suite D., San Diego, CA 92121, USA

Tel: 858-224-2869
Fax: 858-205-1192
info@proteinlounge.com

Institutional License

Need our databases and tools to be availed by your whole university or institute? We recommend signing up for our Site License.

To set up a license, please contact: info@proteinlounge.com

Copyright © Protein Lounge Inc.
   Terms & Conditions